Thermo Fisher Scientific CD200R Polyclonal Antibody
Thermo Fisher Scientific CD200R Polyclonal Antibody는 마우스 CD200R 단백질을 인식하는 염소 유래 IgG 항체로, WB, IHC, ICC/IF, Flow Cytometry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL | View 1 publication |
| Flow Cytometry (Flow) | 2.5 µg per million cells | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse CD200R1 (Thr26–Pro238) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605559 |
Product Specific Information
In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human CD200R is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein. Both receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains.
CD200R is restricted to the surfaces of myeloid lineage cells, and the receptor–substrate interaction may function as a myeloid downregulatory signal.
In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutrophils, but also by T-lymphocytes and mast cells.
Alternative splicing of CD200R results in multiple transcript variants.
Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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