Thermo Fisher Scientific KLF15 Polyclonal Antibody
KLF15 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS와 50% glycerol에 보관되며, 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KLF15 (Accession Q9UIH9), corresponding to amino acid residues M1–H33 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900114 |
Product Specific Information
Antibody detects endogenous levels of total KLF15.
Target Information
KLF15 is a nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family with three C2H2-type zinc fingers. It functions as a transcriptional activator binding to the GA element of the CLCNKA promoter, regulating tissue- and nephron-specific expression of CLCNKA and CLCNKB channel genes. KLF15 plays a key role in adipogenesis via regulation of PPARG expression and acts as an inhibitor of cardiac hypertrophy. It also regulates mitochondrial acetyl-CoA synthase expression in skeletal muscle and may repress photoreceptor-specific gene expression in nonphotoreceptor cells. Expression is high in liver, followed by heart, skeletal muscle, and kidney, but absent in bone marrow or lymphoid tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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