Thermo Fisher Scientific TCCR Polyclonal Antibody
Thermo Fisher Scientific의 TCCR Polyclonal Antibody는 인간 시료에 반응하는 Rabbit IgG 기반 항체로, WB, IHC, ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 10 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152384 |
Product Specific Information
In Western blot applications, this antibody detects a band at approximately 70 kDa.
A suggested positive control is human spleen tissue lysate.
PA5-19984 can be used with blocking peptide PEP-0108.
Target Information
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells and type 2 (Th2) cells, which are critical for cell-mediated immunity and antibody responses.
Th1 differentiation is influenced by IL12, while IL4 influences Th2 differentiation.
Mice deficient in these cytokines, their receptors, or associated transcription factors exhibit impaired Th1 or Th2 immune responses.
The gene discussed encodes a protein similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein.
Diseases associated with IL27RA include Hyper IgE Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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