Thermo Fisher Scientific CD14 Monoclonal Antibody (MEM-15), FITC
CD14 단백질을 인식하는 FITC 결합 Mouse monoclonal 항체로, 인간 및 비인간 영장류 시료에 반응합니다. Flow cytometry에 적합하며, 4°C 암소 보관이 필요합니다. PBS(pH 7.4) 및 0.2% BSA 완충액에 보존되어 있습니다.
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Applications
- Flow Cytometry (Flow): 20 µL / 1×10⁶ cells
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-15 |
| Immunogen | Human urinary proteins from the urine of a patient suffering from proteinuria |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071272 |
Additional Formats
Product Specific Information
This antibody reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein expressed on mature monocytes, macrophages, and neutrophils.
It functions as a multifunctional lipopolysaccharide (LPS) receptor and exists in both membrane-bound and soluble forms.
Soluble CD14 (sCD14) can discriminate structural differences between LPS molecules and contributes to neutralization of serum lipopolysaccharides.
CD14 also binds apoptotic cells and is involved in allergic, inflammatory, and infectious processes.
Alternative splicing yields multiple transcript variants encoding the same CD14 isoform.
Dysfunction of CD14 is associated with diseases such as Mycobacterium chelonae infection and Croup.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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