Thermo Fisher Scientific CD177 Monoclonal Antibody (MEM-166), FITC
CD177 단백질을 인식하는 FITC 결합 Mouse IgG1 단일클론 항체로, 유세포분석(Flow Cytometry)에 적합합니다. 인간 및 비인간 영장류 반응성을 가지며, PBS buffer에 보존되고 4°C 암소 보관이 필요합니다. 연구용으로만 사용됩니다.
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Applications
- Flow Cytometry (Flow): 20 µL / 1×10^6 cells
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-166 |
| Immunogen | Human granulocytes |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071380 |
Additional Formats
- Unconjugated
- Alexa Fluor 647
- APC
- PE
- Request custom conjugation
Product Specific Information
This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of the uPAR family. It is expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes.
Target Information
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein mainly present on neutrophils. Its plasma membrane expression increases during pregnancy, inflammation, or after G-CSF application. CD177 binds to CD31 (PECAM-1) and participates in neutrophil transmigration. Antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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