Thermo Fisher Scientific Growth Hormone (Pituitary Marker) Monoclonal Antibody (GH/3155)
인간 성장호르몬(GH)을 표적하는 단클론 항체로, 뇌하수체 마커 연구에 적합합니다. IHC(P), IHC(PFA), Peptide Array 등 다양한 응용에 사용 가능하며, Protein A/G 정제 및 PBS 버퍼에 보관됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GH/3155 |
| Immunogen | Full-length of human Growth Hormone (GH) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17. These five genes share a remarkably high degree of sequence identity. Alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
HGH is produced by the somatotroph cells in the pituitary and acts through binding to membrane receptors belonging to the cytokine receptor subfamily. Its primary role in stimulating body growth is to induce the liver and other tissues to secrete IGF-1. It promotes both differentiation and proliferation of myoblasts and enhances amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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