Thermo Fisher Scientific ARL2BP Monoclonal Antibody (OTI4E8), TrueMAB

Applications

Tested Application

• Western Blot (WB): 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

ADP-ribosylation factor (ARF)-like proteins (ARLs) are a distinct subgroup of the ARF family of RAS-related GTPases.
The ARL2BP protein binds ARL2·GTP with high affinity but does not interact with ARL2·GDP, activated ARF, or RHO proteins.
Its lack of membrane association upon ARL2 activation suggests a unique function distinct from ARFs.
ARL2BP is considered the first ARL2-specific effector identified, as it interacts with ARL2·GTP but lacks ARL2 GTPase-activating protein activity.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.