Thermo Fisher Scientific SSTR5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SSTR5, validated for WB and IHC(P). Detects human and chimp SSTR5. High specificity with antigen affinity purification. Suitable for research on somatostatin receptor signaling.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.25 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 300–350 of human SSTR5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2271111 |
Product Specific Information
This antibody is predicted to detect chimp somatostatin receptor 5 based on 94% sequence homology.
Suggested positive control: human pancreas cell lysate, human pancreas protein.
Target Information
Somatostatin is a multifunctional protein involved in endocrine and exocrine secretion, neurotransmission, neuronal modulation, and regulation of cell proliferation. These functions are mediated through the somatostatin receptor family, which includes six known receptor subtypes.
SSTR5, a 364 amino acid GPCR protein, is predominantly expressed in the pituitary and hypothalamus. It contains seven transmembrane regions and can form homodimers and heterodimers with SSTR1. SSTR5 complements SSTR2 in regulating ACTH secretion. Polymorphisms in the SSTR5 gene have been observed in patients with acromegaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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