Thermo Fisher Scientific TAB3 Polyclonal Antibody
TAB3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. NF-κB 신호전달 및 자가포식 조절 연구에 적합. 고순도 Protein G 정제, 액상 형태, 안정적 저장 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TAB3 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 50–100 of human TAB3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2140507 |
Target Information
TAB3 functions in the NF-kappaB signal transduction pathway. It, along with TAB2, forms a ternary complex with the protein kinase TAK1 and either TRAF2 or TRAF6 in response to TNF or IL-1 stimulation. TAK1 kinase activity then triggers a signaling cascade leading to activation of NF-kappaB transcription factor.
TAB2 and TAB3 also interact with the autophagy mediator Beclin-1. Upon autophagy induction, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibits autophagy, while their depletion triggers it, suggesting these proteins act as control points for autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.