Thermo Fisher Scientific SERPINA3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

N-terminus of human ACT. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SERPINA3,uniProtId:P01011-1,ncbiNodeId:9606,antigenRange:1,antigenLength:423,antigenImageFileName:PA1-4150_SERPINA3_P01011-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4150_SERPINA3_P01011-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_557416

Product Specific Information

PA1-4150 detects the ACT protein in human samples.

PA1-4150 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~33 kDa protein representing the ACT protein in testis extract.

The PA1- 4150 immunogen is the N-terminus of the human ACT protein.

Target Information

SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer`s disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.