Thermo Fisher Scientific Phospho-PSD-95 (Tyr609) Polyclonal Antibody
Phospho-PSD-95 (Tyr609) 폴리클로날 항체로, 인산화된 PSD-95 단백질을 특이적으로 검출합니다. Western blot에 적합하며, 사람, 생쥐, 랫트 시료에 반응합니다. PBS 기반 완충액에 보관되며 -20°C에서 안정적입니다. 연구용으로만 사용 가능합니다.
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- PA5105606
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DLG4 (Accession P78352), corresponding to amino acid residues around phosphorylated Tyr609 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817034 |
Product Specific Information
This antibody detects endogenous levels of PSD-95 only when phosphorylated at Tyr609.
Target Information
Post Synaptic Density 95 kDa (PSD-95), also known as synapse associated protein 90 kDa (SAP90), is a membrane-associated protein found in the postsynaptic density of forebrain neurons and certain presynaptic structures in the cerebellum. PSD-95 contains three PDZ domains, an SH3 domain, and a guanylate kinase homology (GuK) domain. It plays a role in clustering NMDA receptors and Shaker-type potassium channels at the synaptic membrane in CNS neurons. PSD-95 interacts with other proteins via C-terminal T/SXV motifs or PDZ-PDZ interactions, such as with neuronal nitric oxide synthase (nNOS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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