Thermo Fisher Scientific Ubinuclein 1 Monoclonal Antibody (UBN1-02)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunoprecipitation (IP)

Assay-Dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

UBN1-02

Immunogen

Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Ubinuclein 1,uniProtId:Q9NPG3-1,ncbiNodeId:9606,antigenRange:1-190,antigenLength:1134,antigenImageFileName:MA1-10458_Ubinuclein_1_Q9NPG3-1_House_mouse.svg,antigenImageFileNamePDP:MA1-10458_Ubinuclein_1_Q9NPG3-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11154466

Product Specific Information

This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.

Target Information

Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.