Thermo Fisher Scientific TCR alpha/beta Monoclonal Antibody (IP26), APC
인간 TCR α/β를 인식하는 단클론 항체로, APC 형광표지되어 유세포분석(Flow Cytometry)에 적합합니다. IP26 클론이며, 액상 형태로 PBS(pH 7.4, 0.2% BSA) 용액에 보존됩니다. 4°C 암소 보관, 동결 금지. 연구용 전용 시약입니다.
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Applications
- Flow Cytometry (Flow): 10 µL / 1×10⁶ cells
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IP26 |
| Immunogen | Not available |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157453 |
Available Formats
Product Specific Information
This antibody recognizes a monomorphic extracellular determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood.
Target Information
The T cell antigen receptor (TCR) consists of a ligand-specific alpha/beta heterodimer non-covalently associated with five invariant chains including the CD3 gamma/delta/eta and zeta subunits, all of which are required for efficient surface expression. T cell activation through the TCR induces cellular differentiation and/or proliferation and the production of lymphokines and cytokines.
Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). A small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium and show less TCR diversity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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