Thermo Fisher Scientific NDUFS4 Polyclonal Antibody
NDUFS4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 친화 크로마토그래피 정제 및 PBS/glycerol 완충액에 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–175 of human NDUFS4 (NP_0024861) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805465 |
Product Specific Information
Immunogen sequence:
MAAVSMSVVL RQTLWRRRAV AVAALSVSRV PTRSLRTSTW RLAQDQTQDT QLITVDEKLD ITTLTGVPEE HIKTRKVRIF VPARNNMQSG VNNTKKWKME FDTRERWENP LMGWASTADP LSNMVLTFST KEDAVSFAEK NGWSYDIEER KVPKPKSKSY GANFSWNKRT RVSTK
Positive Samples:
MCF7, HepG2, 293T, Mouse brain, Mouse bone marrow, Mouse liver, Rat brain, Rat liver
Cellular Location:
Matrix side, Mitochondrion inner membrane, Peripheral membrane protein
Target Information
The NDUFS4 gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), also known as NADH:ubiquinone oxidoreductase. Complex I is the first multi-subunit enzyme complex of the mitochondrial respiratory chain and plays a crucial role in ATP production. It transfers electrons from NADH to ubiquinone through a series of redox reactions, generating a proton gradient across the inner mitochondrial membrane that drives ATP synthesis. Complex I comprises at least 41 subunits, with 7 encoded by mitochondrial DNA and the remainder by nuclear genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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