Thermo Fisher Scientific MDH2 Polyclonal Antibody
Thermo Fisher Scientific의 MDH2 Polyclonal Antibody는 인간 및 마우스 시료에 반응하며, Western blot과 ELISA에 적합합니다. 재조합 단백질 항원을 사용하여 제작되었으며, 미토콘드리아 내 MDH2 단백질 검출에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 59–338 of human MDH2 (NP_005909.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.42 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805463 |
Product Specific Information
Immunogen sequence:
AHTPGVAADL SHIETKAAVK GYLGPEQLPD CLKGCDVVVI PAGVPRKPGM TRDDLFNTNA TIVATLTAAC AQHCPEAMIC VIANPVNSTI PITAEVFKKH GVYNPNKIFG VTTLDIVRAN TFVAELKGLD PARVNVPVIG GHAGKTIIPL ISQCTPKVDF PQDQLTALTG RIQEAGTEVV KAKAGAGSAT LSMAYAGARF VFSLVDAMNG KEGVVECSFV KSQETECTYF STPLLLGKKG IEKNLGIGKV SSFEEKMISD AIPELKASIK KGEDFVKTLK
Positive Samples: 293T, HepG2, Jurkat, A-549, MCF7, HeLa, Mouse kidney, Mouse heart, Mouse skeletal muscle
Cellular Location: Mitochondrion matrix
Target Information
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.
[provided by RefSeq, Sep 2013]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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