Thermo Fisher Scientific v-Myb Polyclonal Antibody
Human 및 Mouse 시료에서 v-Myb 단백질을 검출하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 버퍼에 보관하며 -20°C에서 안정적. 연구용으로만 사용 가능.
- 카탈로그번호
- PA549784
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human MYB-A (aa 231–280) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635237 |
Product Specific Information
This antibody detects endogenous levels of total MYBL1 protein.
Target Information
A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells, where they inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest mediated by p21, while A-Myb acts as an anti-apoptotic factor by activating the bcl-2 promoter and upregulating Bcl-2 expression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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