Thermo Fisher Scientific HGK Polyclonal Antibody
HGK/MAP4K4 단백질을 검출하는 Thermo Fisher Scientific의 다클론 항체. Western blot 및 면역형광(ICC/IF)에 사용 가능. 인간 및 생쥐 반응성, 항원 친화 크로마토그래피로 정제. 액상 형태, -20°C 보관.
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human MEKKK 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635233 |
Product Specific Information
This antibody detects endogenous levels of total HGK / MAP4K4 protein.
Target Information
MAP4K4 (HGK) is a serine/threonine kinase involved in stress-activated MAPK signaling pathways and responses to environmental stress and cytokines such as TNF-alpha. It acts upstream of the JUN N-terminal pathway and interacts with adapter proteins Nck via its SH3 domain. HGK binds through its CNH regulatory domain to the N-terminal region of SPG3A. Expression is ubiquitous across tissue types; isoform 5 is abundant in the brain, while isoform 4 is predominant in liver, skeletal muscle, and placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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