
Thermo Fisher Scientific CXCL13 Polyclonal Antibody
CXCL13 단백질을 인식하는 Goat Polyclonal 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 trehalose 완충액에 보존. 인간 시료 반응성으로 연구용에 최적화됨.
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Thermo Fisher Scientific CXCL13 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | - |
| Immunohistochemistry (IHC) | - | 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL | 1 publication |
| Immunocytochemistry (ICC/IF) | - | 2 publications |
| Neutralization (Neu) | 1–4 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human CXCL13/BCA-1 (Val23–Arg94) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610228 |
Product Specific Information
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in secondary lymphoid organs. It promotes migration of B lymphocytes (both B-1 and B-2) to follicles of the spleen, lymph nodes, and Peyer’s patches.
Produced by macrophages, with high expression in large peritoneal macrophages, Kupffer cells, and lung macrophages (both CD11c+ and CD11c-).
Its receptor, CXCR5 (BLR-1), is expressed on B cells, Tfh cells, and some memory T cells.
CXCL13 plays a role in chronic lymphocytic leukemia (CCL) and serves as a plasma biomarker for germinal center activity and broadly neutralizing antibody generation against HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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