Thermo Fisher Scientific Myostatin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1 µg/mL

-

Immunohistochemistry (Frozen) (IHC (F))

5-15 µg/mL

-

Neutralization (Neu)

0.6-3 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived recombinant mouse GDF-8/Myostatin Asp268-Ser376 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Myostatin,uniProtId:O08689-1,ncbiNodeId:10090,antigenRange:268-376,antigenLength:376,antigenImageFileName:PA5-47034_Myostatin_O08689-1_Goat.svg,antigenImageFileNamePDP:PA5-47034_Myostatin_O08689-1_Goat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2610426

Product Specific Information

In Western blots, approximately15% cross-reactivity is observed with recombinant human/mouse/rat GDF-11. In direct ELISAs, this antibody shows approximately 5% cross-reactivity with recombinant mouse (rm) GDF-5 and rmGDF-6.

Reconstitute at 0.2 mg/mL in sterile PBS.

Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

The protein encoded by this gene is a member of the bone morphogenetic protein family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.