Thermo Fisher Scientific Phospho-p41-ARCb (Thr21) Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal 항체로, Phospho-Arpc1b/p41-Arc (Thr21)를 인식합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5143652
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phospho-Arpc1b/p41-Arc (Thr-21) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding threonine 21 in human Arpc1b. This peptide sequence is highly conserved in rat, mouse, chicken, and fish Arpc1b, and has some homology to the conserved site in isoform Arpc1a. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2942880 |
Product Specific Information
The antibody detects a 41 kDa protein corresponding to the molecular mass of Arpc1b on SDS-PAGE immunoblots of human A431 and mouse C2C12 treated with calyculin A. This reactivity is removed with lambda phosphatase treatment.
Target Information
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. Both proteins may function as the p41 subunit of the human Arp2/3 complex, which is involved in actin polymerization control. The p41 subunit may contribute to assembling and maintaining the Arp2/3 complex structure, adapting its function to various cell types or developmental stages. It also plays a role in centrosomal homeostasis as an activator and substrate of Aurora A kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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