Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI3A12), TrueMAB

Applications

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

• For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
• For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily.
It functions as a lymphocyte inhibitory receptor, regulating immune responses by inhibiting lymphocyte activation.
BTLA is constitutively expressed on most CD4⁺ and CD8⁺ T cells and decreases upon T cell activation, remaining on Th1 but not Th2 cells.
It interacts with HVEM (herpesvirus entry mediator), a TNF receptor superfamily member, playing a key role in lymphocyte activation and immune homeostasis.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.