Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI3A12), TrueMAB
인간 BTLA 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Flow Cytometry에 사용 가능. 동결건조 형태로 제공되며, PBS와 trehalose 완충액에 보관. 연구용으로만 사용 가능하며, 재구성 및 결합 실험에 적합.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 31–157 + Mouse Fc of human BTLA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily.
It functions as a lymphocyte inhibitory receptor, regulating immune responses by inhibiting lymphocyte activation.
BTLA is constitutively expressed on most CD4⁺ and CD8⁺ T cells and decreases upon T cell activation, remaining on Th1 but not Th2 cells.
It interacts with HVEM (herpesvirus entry mediator), a TNF receptor superfamily member, playing a key role in lymphocyte activation and immune homeostasis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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