Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI8B6), TrueMAB
인간 BTLA(CD272)에 특이적인 Mouse IgG1 단클론 항체로 Flow Cytometry에 적합. 무보존제 Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 면역반응 조절 연구용으로 적합하며, 연구용으로만 사용 가능.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 31–157 + Mouse Fc of human BTLA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor of the CD28 superfamily. It acts as a lymphocyte inhibitory receptor, regulating immune responses by inhibiting lymphocyte activation.
BTLA is constitutively expressed on most CD4+ and CD8+ T cells, with expression decreasing upon activation. It remains on Th1 cells but not Th2 cells.
BTLA interacts with HVEM (herpesvirus entry mediator), a TNF receptor superfamily member, forming a key pathway that regulates lymphocyte activation and immune homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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