Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI2C2), TrueMAB
BTLA 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Flow Cytometry에 적합합니다. 동결건조 형태로 제공되며, PBS 버퍼와 트레할로스 함유. 연구용으로 사용되며, 재구성 시 1 mg/mL 농도로 조제 가능합니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 31–157 + Mouse Fc of human BTLA produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily. It functions as a lymphocyte inhibitory receptor that modulates immune responses.
BTLA is constitutively expressed on most CD4⁺ and CD8⁺ T cells, with expression decreasing upon activation. It remains expressed on Th1 cells but not Th2 cells.
BTLA interacts with the TNFR superfamily member HVEM (herpesvirus entry mediator), playing a key role in regulating lymphocyte activation and homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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