Thermo Fisher Scientific Human Precerebellin Synthetic Peptide
Human Precerebellin 합성 펩타이드로, 항체 차단용으로 사용 가능. 인간 유래 단백질 반응성, 액상 형태, 200 µg/mL 농도. 연구용으로만 사용되며, -20°C에서 보관.
- 카탈로그번호
- PEP0279
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the center of human Precerebellin.
PEP-0279 can be used as a blocking peptide with polyclonal antibody PA5-20160.
Target Information
Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin possesses functions other than those already stated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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