Thermo Fisher Scientific HLA-DR/DQ Monoclonal Antibody (49.1), FITC

Applications

• Flow Cytometry (Flow)

Tested Dilution: 1:10
Publications: -

Product Specifications

Product Specific Information

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.

Target Information

The major histocompatibility complex (MHC) is a cluster of genes important in the immune response to infections. In sheep, this complex is referred to as the ovine leukocyte antigen (OLA) region.
There are two major types of MHC class IIa molecules encoded by the OLA, DR and DQ, each composed of an alpha and beta chain.
The polymorphic epitope on ovine MHC class II DQ and DR molecules is constitutively expressed on antigen-presenting cells such as dendritic cells, B lymphocytes, monocytes, macrophages, activated T lymphocytes, and may be induced on other cell types by interferon gamma.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지