Thermo Fisher Scientific B7-H3 (CD276) Polyclonal Antibody
Human B7-H3 (CD276) 단백질을 인식하는 Goat Polyclonal 항체. Western blot에 적합하며, 0.1–3 µg/mL 농도로 사용 가능. 0.5 mg/mL 액상 형태로 제공되며, TBS(pH 7.3) + 0.5% BSA 용액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–3 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KHSDSKEDDGQE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933948 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
CD276 (B7-H3) is a member of the B7 family of co-stimulatory molecules. It is a type I transmembrane protein that induces proliferation of CD4⁺ and CD8⁺ T cells, enhances cytotoxic T cell generation, and selectively stimulates interferon gamma production.
Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines and is also widely expressed in peripheral tissues such as heart, kidney, testis, and colon.
In humans, CD276 exists as two isoforms resulting from gene duplication and differential splicing. CD276 has potential therapeutic significance in regulating cell-mediated immune responses to cancer, particularly in combination with anti-angiogenic therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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