Thermo Fisher Scientific DYNLT1 Polyclonal Antibody
DYNLT1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용 가능. E. coli 유래 DYNLT1 항원을 면역원으로 사용하며, 고순도 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Thermo Fisher Scientific DYNLT1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| Flow Cytometry (Flow) | 1–3 µg / 1×10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human DYNLT1 recombinant protein (Position: M1–A80) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746293 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
DYNLT1 acts as a non-catalytic accessory component of the cytoplasmic dynein 1 complex, linking dynein to cargos and adapter proteins that regulate dynein function. It plays a role in intracellular retrograde motility of vesicles and organelles along microtubules. Also involved in cargo transport such as rhodopsin-bearing vesicles in polarized epithelia, and in targeting D-type retrovirus gag polyproteins to cytoplasmic assembly sites. DYNLT1 may function in neuronal morphogenesis by regulating actin cytoskeleton through Rac1 activation, and may act as a receptor-independent activator of heterotrimeric G-protein signaling. It plays roles in neurogenesis and mitotic spindle orientation regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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