Thermo Fisher Scientific Desmoglein 3 Polyclonal Antibody
Human Desmoglein 3 인식 Rabbit Polyclonal Antibody로, Western blot에 최적화된 연구용 시약입니다. 항원 친화 크로마토그래피로 정제되었으며, Lyophilized 형태로 제공됩니다. 세포 간 결합 연구 및 pemphigus vulgaris 관련 연구에 적합합니다.
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Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 3 (981–999aa QLRGSHTMLCTEDPCSRLI) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746288 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Desmoglein 3 (Dsg3), also known as Cadherin family member 6 (CDHF6), is a desmosomal cadherin family protein critical for cell-cell adhesion. It is mainly expressed in stratified squamous epithelium such as skin, oral mucosa, and esophagus. Desmoglein 3 is identified as the autoantigen of pemphigus vulgaris (PV), an autoimmune disease causing blister formation due to loss of cell adhesion.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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