Thermo Fisher Scientific CD45RO Monoclonal Antibody (UCHL1), APC
CD45RO 단백질을 인식하는 UCHL1 클론의 APC 형광 표지 단일클론 항체. 인간 시료에 반응하며 Flow Cytometry, IHC, ICC/IF에 사용 가능. 메모리/활성화 T세포 및 흉선세포 표지에 적합. 4°C 보관, 동결 금지.
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Thermo Fisher Scientific CD45RO Monoclonal Antibody (UCHL1), APC
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 7 publications |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | 10 µL / 1×10⁶ cells | View 3 publications |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UCHL1 |
| Immunogen | Human IL-2 dependent T cells |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1955321 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD45RO, a 180 kDa low molecular weight isoform of the leukocyte common antigen (LCA).
The antigen is expressed on a subset of memory/activated T cells and on cortical thymocytes.
Target Information
CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein.
CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases.
It promotes cell survival by modulating integrin-mediated signal transduction and is involved in DNA fragmentation during apoptosis.
CD45RO is expressed on macrophages, CD8⁺ T cells, activated T cells, and myeloma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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