Thermo Fisher Scientific CD4 Monoclonal Antibody (MEM-241), PerCP

Applications

• Flow Cytometry (Flow): 10 µL / 1×10⁶ cell suspension
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Product Specifications

Additional Formats

• Unconjugated
• APC
• Biotin
• FITC
• PE
• Request custom conjugation

Product Specific Information

This antibody recognizes an extracellular epitope of the CD4 antigen, a 55 kDa transmembrane glycoprotein expressed on a subset of T lymphocytes (“helper” T-cells), as well as on monocytes, tissue macrophages, and granulocytes.

Target Information

The CD4 antigen is involved in the recognition of MHC class II molecules and serves as a co-receptor for HIV. It is primarily expressed in T helper cells but may also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression occurs in thymus, lymph nodes, tonsils, spleen, and certain non-lymphoid tissues such as brain and gut.
CD4 plays a key role in T-cell activation through association with the T-cell receptor complex and Lck kinase, and may mediate neuronal damage in immune-related CNS diseases.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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