Thermo Fisher Scientific MSI2 Polyclonal Antibody
MSI2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot, IHC, ICC, Flow cytometry에 사용 가능하며, 인체 MSI2 단백질(aa 1-185)을 면역원으로 제작되었습니다. 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol buffer로 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human MSI2 (aa 1–185) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854617 |
Product Specific Information
Positive Control:
SW480, K562, HepG2, PC-12, SH-SY5Y, rat epididymis tissue, human breast tissue, human placenta tissue, mouse brain tissue.
Target Information
Msi2 (Musashi homolog 2), also known as MSI2H, is a 328 amino acid cytoplasmic RNA-binding protein containing two RRM (RNA recognition motif) domains.
It is expressed ubiquitously at low levels and regulates target mRNA expression, contributing to stem cell proliferation and maintenance in the central nervous system.
Msi2 undergoes posttranslational phosphorylation and is upregulated after brain injury, suggesting a role in neural regeneration.
Chromosomal aberrations involving the Msi2 gene are linked to the progression of chronic myeloid leukemia.
Multiple isoforms exist due to alternative splicing.
Tissue specificity: Ubiquitous; detected at low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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