Thermo Fisher Scientific AMACR Polyclonal Antibody
Rabbit polyclonal antibody targeting human AMACR for WB, IHC, ICC/IF, and Flow applications. Validated for multiple tissues including kidney and liver. Supplied as 1 mg/mL liquid, affinity purified, in PBS with glycerol and BSA. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human AMACR (aa 1–382) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854618 |
Product Specific Information
Positive Control: Human kidney tissue, mouse liver tissue lysate, Siha, SW480, HepG2, human liver tissue, human colon cancer tissue, PC-3M.
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme involved in the β-oxidation of branched-chain fatty acids. High expression of P504S protein is observed in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining of paraffin-embedded tissue. Expression is also detected in premalignant lesions such as high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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