Thermo Fisher Scientific Human EVER2 Synthetic Peptide
인간 EVER2 단백질의 N-말단 14 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20527과 함께 차단 실험용으로 사용 가능. PBS(pH 7.2)와 0.1% BSA 포함, −20°C 보관. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the amino terminus of human EVER2.
PEP-0647 can be used as a blocking peptide with polyclonal antibody PA5-20527.
Target Information
Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes, EVER1 and EVER2, cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulate higher levels of zinc in the nucleolus and nucleus compared to those with an intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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