Thermo Fisher Scientific MTHFR Monoclonal Antibody (OTI4C5), TrueMAB
MTHFR 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, IgG1 아이소타입입니다. 동결건조 형태로 제공되며, PBS buffer에 trehalose가 포함되어 안정성이 우수합니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–230 of human MTHFR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The MTHFR protein catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
Genetic variations in this gene are associated with susceptibility to occlusive vascular disease, neural tube defects, colon cancer, and acute leukemia.
Mutations can lead to methylenetetrahydrofolate reductase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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