Thermo Fisher Scientific MMP11 Monoclonal Antibody (OTI2D7), TrueMAB
인간 MMP11 단백질(아미노산 239-488)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 적합하며, 동결건조 형태로 제공. 연구용으로만 사용 가능하며, 재용해 및 탈염 후 결합 실험에 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 239–488 of human MMP11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Stromelysin (MMP-11) is a matrix metalloproteinase with broad substrate specificity, capable of degrading proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen.
The stromelysin-3 (MMP-11) gene is expressed specifically in stromal cells surrounding invasive breast carcinomas and is localized on chromosome 22q.
MMP-11 expression is more pronounced in malignant tumors compared to benign ones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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