Thermo Fisher Scientific Cytokeratin 6 (KRT6) (Basal Cell Marker) Monoclonal Antibody (KRT6/1702)
Cytokeratin 6 단백질을 인식하는 단클론 항체로, 기저세포 및 과증식성 각질형성세포의 표지에 사용됩니다. 사람과 생쥐 시료에 반응하며, IHC(P) 및 IHC(PFA) 실험에 적합합니다. 단백질 A/G로 정제된 액상 형태로 제공되며, 4°C에서 보관합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunohistochemistry (PFA fixed) (IHC (PFA)): 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT6/1702 |
| Immunogen | Recombinant human keratin 6 protein (Cytokeratin 6, UniProt IDs: P02538-1, P48668-1, P04259-1; antigen range: 1–564 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins).
Keratin 6 is found in hair follicles, suprabasal cells of internal stratified epithelia, and epidermis, both in normal and hyperproliferative states.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas, and its expression is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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