Thermo Fisher Scientific GluR1 Monoclonal Antibody (N355/1), PerCP
GluR1 단백질 검출용 PerCP 결합 단일클론 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 단백질 G 정제, 보존제 무첨가. 4°C 보관, 신경전달 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N355/1 |
| Immunogen | Fusion protein amino acids 1–389 (extracellular N-terminus) of rat GluA1/GluR1 |
| Conjugate | PerCP |
| Excitation/Emission Max | 482/675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932083 |
Additional Formats
Product Specific Information
- 1 µg/mL of MA5-45629 was sufficient for detection of GluA1/GluR1 in 20 µg of mouse brain membrane lysate by colorimetric immunoblot using goat anti-mouse IgG:HRP as secondary antibody.
- Detects approximately 100 kDa.
- Does not cross-react with GluR2.
- This antibody was formerly sold as clone S355-1.
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformational change that opens the cation channel, converting the chemical signal into an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization characterized by delayed accumulation of current flux upon continued application of glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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