Thermo Fisher Scientific GluR1 Monoclonal Antibody (N355/1), FITC
GluR1 단백질을 인식하는 FITC 결합 단클론 항체로, 인간, 마우스, 랫트에 반응합니다. Western blot, IHC, ICC/IF에 적합하며, 단백질 G로 정제된 액상 형태입니다. 4°C 암소 보관, 형광 분석용으로 연구 전용입니다.
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- MA545628
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N355/1 |
| Immunogen | Fusion protein amino acids 1–389 (extracellular N-terminus) of rat GluA1/GluR1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.09 mM sodium bicarbonate/PBS, pH 7.4, with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932082 |
Additional Formats Available
- Unconjugated (MA5-27694)
- APC (MA5-45627)
- PE (MA5-45630)
- PerCP (MA5-45629)
- Custom conjugation available upon request
Product Specific Information
- 1 µg/mL of MA5-45628 was sufficient for detection of GluA1/GluR1 in 20 µg of mouse brain membrane lysate using colorimetric immunoblot analysis with goat anti-mouse IgG:HRP as secondary antibody.
- Detects approximately 100 kDa.
- Does not cross-react with GluR2.
- Formerly sold as clone S355-1.
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformational change that opens the cation channel, converting the chemical signal to an electrical impulse. The receptor desensitizes rapidly and enters a transient inactive state. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization characterized by delayed current flux accumulation upon continued glutamate application.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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