Thermo Fisher Scientific TCR alpha/beta Monoclonal Antibody (IP26), Alexa Fluor 700, eBioscience
인간 TCR α/β 체인을 인식하는 IP26 단클론 항체로, Alexa Fluor 700 형광체가 결합되어 있습니다. 유세포분석(Flow Cytometry)에 최적화되어 있으며, 적색 레이저(633–647 nm)에서 여기되어 723 nm에서 방출됩니다. 고순도 정제 및 안정적인 PBS 버퍼로 제공됩니다.
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Thermo Fisher Scientific TCR alpha/beta Monoclonal Antibody (IP26), Alexa Fluor 700, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.5 µg)/test
Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Alexa Fluor™ 700, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IP26 |
| Conjugate | Alexa Fluor™ 700 |
| Excitation / Emission Max | 696 / 719 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2815261 |
Available Formats
- Unconjugated
- APC
- APC-eFluor 780
- Biotin
- eFluor 450
- FITC
- NovaFluor Blue 510
- NovaFluor Blue 610-70S
- NovaFluor Red 710
- NovaFluor Yellow 590
- NovaFluor Yellow 610
- NovaFluor Yellow 660
- PE
- PE-Cyanine5
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 780
- Request custom conjugation
Product Specific Information
The IP26 monoclonal antibody reacts with the alpha beta chain of human TCR. The alpha beta TCR is expressed by the majority of peripheral T cells.
Applications Reported: Flow cytometric analysis
Applications Tested: Tested by flow cytometric analysis of normal human peripheral blood cells; use at 5 µL (0.5 µg) per test.
A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL.
Cell number should be determined empirically (10⁵–10⁸ cells/test).
Fluorochrome Information:
Alexa Fluor 700 emits at 723 nm and can be excited with the red laser (633–647 nm).
Recommended optical setup: 685 LP mirror and 710/20 band pass filter.
Ensure instrument compatibility.
Excitation: 633–647 nm
Emission: 723 nm
Laser: Red Laser
Target Information
The T cell antigen receptor (TCR) consists of a ligand-specific alpha/beta heterodimer associated with invariant CD3 subunits (gamma, delta, eta, zeta). These are essential for surface expression and intracellular signal transduction. TCR activation induces T cell differentiation, proliferation, and cytokine production.
Most human T cells express TCR alpha/beta and either CD4 or CD8 molecules. Gamma/delta T cells are primarily found in epithelial tissues and exhibit distinct antigen recognition.
Defects or mutations in TCR components are associated with autoimmune diseases, immunodeficiency, and tumor-related responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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