
Thermo Fisher Scientific TNNT2 Monoclonal Antibody (OTI7D2), TrueMAB
인간 TNNT2 단백질을 인식하는 Mouse IgG2b 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 PBS/BSA/glycerol 버퍼에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D2 |
| Immunogen | Full length human recombinant protein of human TNNT2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, located on the thin filament of striated muscles. It regulates muscle contraction in response to intracellular calcium ion concentration changes and is essential for proper muscle function and myofibril formation. In humans, four cTnT isoforms are expressed in a developmentally regulated manner, and their expression is affected by heart failure. Mutations in Cardiac Troponin T have been linked to familial hypertrophic cardiomyopathy and dilated cardiomyopathy. The gene undergoes alternative splicing, resulting in multiple tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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