Thermo Fisher Scientific ATXN7L1 Monoclonal Antibody (OTI4F6), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:4,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

ATXN7L1 (ataxin-7-like protein 1) is an 833 amino acid protein containing one SCA7 domain.
The ATXN7L1 gene is conserved across chimpanzee, canine, mouse, rat, and chicken, and maps to human chromosome 7q22.3.
Chromosome 7 (~158 million bases) encodes over 1,000 genes and represents about 5% of the human genome.
It is associated with several genetic conditions including:

• Osteogenesis imperfecta
• Pendred syndrome
• Lissencephaly
• Citrullinemia
• Shwachman-Diamond syndrome
  Deletion in chromosome 7q is linked to Williams-Beuren syndrome, characterized by mild mental retardation, friendliness with strangers, and distinctive facial features.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.

제품 이미지