Thermo Fisher Scientific ATXN7L1 Monoclonal Antibody (OTI3G10), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

ATXN7L1 (ataxin-7-like protein 1) is an 833 amino acid protein containing one SCA7 domain. The gene is conserved in chimpanzee, canine, mouse, rat, and chicken, and maps to human chromosome 7q22.3.
Chromosome 7, approximately 158 million bases long, encodes over 1,000 genes and comprises about 5% of the human genome. It has been associated with disorders such as osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia, and Shwachman-Diamond syndrome.
Deletion of part of the q arm of chromosome 7 is linked to Williams-Beuren syndrome, characterized by mild mental retardation, friendliness with strangers, and an elfin facial appearance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.