
Thermo Fisher Scientific MC5R Polyclonal Antibody
Rabbit polyclonal antibody targeting human MC5R for IHC applications. Recognizes melanocortin receptor involved in thermoregulation and immunomodulation. High specificity and purity via antigen affinity chromatography. Supplied as 1 mg/mL liquid in PBS...
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- PA533928
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 7.6–8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from N-terminal extracellular domain of human MC5 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551296 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla (100%)
Bat, Panda (94%)
Monkey, Marmoset, Rabbit (89%)
Target Information
MC5R (Melanocortin Receptor 5) mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH), activating adenylate cyclase. It regulates various physiological functions such as:
- Thermoregulation
- Immunomodulation
- Appetite control
- Sexual behavior
MC5R is expressed in multiple tissues including pituitary, exocrine glands, reproductive organs, lung, kidney, and esophagus. No human ESTs have been isolated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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