Thermo Fisher Scientific SIT Monoclonal Antibody (SIT-01), PE
PE 형광으로 표지된 SIT-01 단클론 항체로 인간 SIT 단백질 검출에 적합. Flow Cytometry 응용 가능. 고순도 Size-exclusion chromatography로 정제. 4°C 암소 보관, 동결 금지. 연구용으로만 사용.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1–5 µg/mL
Publications: - (none listed)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SIT-01 |
| Immunogen | Bacterially produced recombinant intracellular fragment of human SIT |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2189052 |
Additional Formats
Product Specific Information
This antibody reacts with murine SIT.
Target Information
SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and development. Binding to Grb2 plays a pivotal role in signal transduction.
Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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