Thermo Fisher Scientific Annexin A1 Polyclonal Antibody
Annexin A1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, IP 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 2 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | – |
| Immunoprecipitation (IP) | 1:100–1:500 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 24–346 of Human Annexin A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.95 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.0, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2544791 |
Product Specific Information
- Recommended positive controls: HeLa, NIH-3T3, JC, ANXA1-transfected 293T
- Predicted reactivity: Mouse (86%), Rat (88%), Dog (91%), Pig (88%), Rabbit (91%), Chimpanzee (100%), Bovine (90%)
- Store product as a concentrated solution; centrifuge briefly prior to opening the vial.
Target Information
Annexin I belongs to a family of Ca²⁺-dependent phospholipid-binding proteins located on the cytosolic face of the plasma membrane. It has a molecular mass of 40 kDa and exhibits phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of inflammatory mediators such as prostaglandins and leukotrienes, Annexin I may have potential anti-inflammatory activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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