Thermo Fisher Scientific BDNF Recombinant Superclonal Antibody (19HCLC)

Applications

• Western Blot (WB): 1–3 µg/mL
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Product Specifications

Product Specific Information

This antibody is predicted to react with non-human primate, rat, and rabbit based on sequence homology.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are composed of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies, while maintaining consistency through recombinant production.

Functionally similar to polyclonal antibodies, they recognize multiple epitope sites and provide higher detection sensitivity for low-abundance targets. Each lot contains a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability.

Note: Formerly called “Recombinant Polyclonal Antibody”, now rebranded as “Recombinant Superclonal™ Antibody”. Physical product and performance remain unchanged.

Target Information

BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. It is synthesized as pre-proBDNF, cleaved to proBDNF, and further processed into the mature 14 kDa protein. Both proBDNF and mature BDNF are biologically active and secreted in synaptic vesicles.

BDNF is widely expressed in the central nervous system, acting through TrkB and p75-NTR receptors to promote neuronal survival, differentiation, and synaptic regulation. It plays critical roles in memory formation and neuronal plasticity. Reduced BDNF expression has been observed in Alzheimer’s and Huntington’s disease, and it may influence stress response and mood regulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.