Thermo Fisher Scientific IFN alpha Recombinant Superclonal Antibody (9HCLC)

Applications

• Western Blot (WB): 1–2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with non-human primate based on sequence homology.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds — the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies — all delivered with the consistency only found in a recombinant antibody.

While functionally similar to a polyclonal antibody — recognizing multiple epitope sites on the target and producing higher detection sensitivity for low-abundance targets — a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be reproduced in every lot, eliminating biological variability typically associated with polyclonal antibody production.

Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor components results in activation of multiple signaling pathways involved in innate immune responses against viral infection.

In humans, the gene for IFN alpha is located on chromosome 9. Type I interferons consist of 14 different alpha isoforms, and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species, including rats, mice, birds, reptiles, and fish.

IFN alpha is produced primarily by plasmacytoid dendritic cells, acts as a potent component of the antiviral innate immune response, and modulates adaptive immunity. Dysfunction of IFN alpha is associated with diseases such as Hepatitis C and Hepatitis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.