Thermo Fisher Scientific ERK1/ERK2 Recombinant Superclonal Antibody (3HCLC)
ERK1/ERK2 단백질을 인식하는 Recombinant Superclonal 항체로, 높은 특이성과 재현성을 제공합니다. Western blot 및 ChIP assay에 적합하며, 인간 및 설치류 시료에 반응합니다. 재조합 토끼 IgG 형식으로, 단백질 A 정제 및 PBS 버퍼에 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 2 publications |
| ChIP assay (ChIP) | 1 µL | — |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 3HCLC |
| Immunogen | Peptide corresponding to amino acids 293–315 of human extracellular signal regulated kinase 1/2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532630 |
Product Specific Information
This antibody is predicted to react with equine, mouse, and rat based on sequence homology.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies, providing the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
Unlike traditional polyclonal antibodies, these Superclonal™ antibodies have a defined mixture of heavy and light chains, ensuring batch-to-batch reproducibility.
Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. The product and performance remain unchanged.
Target Information
ERK1 and ERK2 are widely expressed kinases involved in regulating meiosis, mitosis, and postmitotic functions in differentiated cells.
They are activated by various stimuli, including growth factors, cytokines, viral infection, and G protein-coupled receptor ligands.
Upon activation, ERK1/2 phosphorylate cytoplasmic and nuclear targets such as transcription factors c-Fos and Elk-1, mediating key signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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