Thermo Fisher Scientific ARHGEF4 Monoclonal Antibody (ARHGEF-08)
인간 ARHGEF4 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 Flow cytometry에 사용 가능. Recombinant fragment(aa 143-271)를 면역원으로 사용하며 Protein A로 정제됨. 액상 형태, 1 mg/mL 농도, 4°C 보관.
- 카탈로그번호
- MA528622
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- pk
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ARHGEF-08 |
| Immunogen | Recombinant fragment of human ARHGEF4 (amino acids 143–271) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745581 |
Product Specific Information
This antibody recognizes human intracellular protein ARHGEF4 / ASEF1, an approximately 80 kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42. The epitope is located near the SH3 domain region.
Target Information
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli through G protein-coupled receptors. The encoded protein may form complexes with G proteins and stimulate Rho-dependent signaling. This protein is similar to rat collybistin. Alternative splicing generates two transcript variants encoding different isoforms, with potential use of multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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