Thermo Fisher Scientific ARHGEF4 Monoclonal Antibody (ARHGEF-08), PE
인간 ARHGEF4 단백질을 인식하는 단클론 항체로, PE 형광 표지되어 유세포분석에 적합합니다. Rac1 및 Cdc42 특이적 GEF 단백질 검출에 사용됩니다. 4°C 어둠에서 보관하며 동결 금지. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA528621
- 판매단위
- pk
카탈로그
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Applications
- Flow Cytometry (Flow): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ARHGEF-08 |
| Immunogen | Recombinant fragment of human ARHGEF4 (amino acids 143–271) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745580 |
Additional Formats
Product Specific Information
This antibody recognizes human intracellular protein ARHGEF4 / ASEF1, approximately 80 kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42.
The epitope is located near the SH3 domain region.
Target Information
Rho GTPases are key regulators of cellular processes triggered by extracellular stimuli via G protein-coupled receptors.
ARHGEF4 may form complexes with G proteins to stimulate Rho-dependent signaling.
This protein shares similarity with rat collybistin and has two transcript variants encoding different isoforms.
Multiple polyadenylation sites may exist for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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